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LAS VEGAS - SEPTEMBER 12: Actor George Eads (L) and actress Jorja Fox arrive at the grand opening of the CSI: The Experience attraction at MGM Grand Hotel/Casino September 12, 2009 in Las Vegas, Nevada. (Photo by Ethan Miller/Getty Images for EMS Exhibits)

LOS ANGELES (AP) — William Petersen and Jorja Fox are reuniting to solve crimes in “CSI: Vegas.” The CBS series premiering on Oct. 6 brings their characters of Gil Grissom and Sara Sidle back together 21 years after they first debuted in “CSI: Crime Scene Investigation.” Petersen and Fox say science has changed so much that they were rusty in handling equipment on set. Fox says the world is more topsy-turvy than it was in 2000, so working with Petersen again is reassuringly familiar. The new show is set in Las Vegas like the old one, although there’s new characters for Petersen and Fox to interact with.